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Cosequin ASU with MSM(Nutramax) Tasty Apple Flavored Powder combines our proprietary glucosamine hydrochloride and low molecular weight chondroitin sulfate with an innovative supplement agent, ASU (avocado/soybean unsaponifiables), and MSM.

MOST VETS SELL THIS PRODUCT IN THE $209 - $239 RANGE

Avocado Soybean Unsaponifiable (ASU) Extracts Earn a Passing Grade for Equine Osteoarthritis
by: Stacey Oke, DVM, MSc
July 30, 2007

Avocado and soybean unsaponifiable (ASU) extracts--the fraction of oil that does not form soap after hydrolysis--are some of the newest joint products to grace the equine nutritional supplement shelves. The beneficial effects of ASU for horses with osteoarthritis were reported in a new study by David Frisbie, DVM, PhD and colleagues from the Gail Holmes Equine Orthopaedic Research Center at Colorado State University.

The researchers evaluated ASU in horses with experimentally-induced osteoarthritis. This clinical trial concluded that ASU significantly reduced the severity of joint damage and significantly increased the synthesis of cartilage glycosaminoglycans (i.e., the building blocks of articular cartilage) in joints with osteoarthritis, compared to horses treated with a placebo.

In this study, 16 horses with osteoarthritis were divided into two groups: eight horses received ASU extracts in molasses and eight received only molasses for 70 days. During the study, the horses were exercised on a treadmill and the researchers measured the horses' lameness, joint swelling, and various gross, microscopic, and biochemical parameters.

While ASU did not decrease clinical signs of pain in horses with osteoarthritis, a disease-modifying effect was identified suggesting that oral administration of ASU can be useful in the management of horses with osteoarthritis, Frisbie reported.

Nutramax ''research has shown that the combination of ASU plus glucosamine and chondroitin sulfate performs, in vitro, superior to the combination of glucosamine and chondroitin sulfate alone,'' said Carmelita G. Frondoza, Ph.D., director of research and development, Nutramax Laboratories, Inc.

Cosequin ASU is a dual synergistic formula with glucosamine interacting synergistically with both chondroitin sulfate and ASU.

''The science behind Cosequin ASU is a major factor differentiating it from the competition, ''said Barbara Eves, DVM, senior manager of scientific communications. ''The inclusion of ASU with our researched glucosamine and low molecular weight chondroitin sulfate sets this product apart from other joint health supplements and establishes a new benchmark of joint health support '' Additionally, MSM is included at 10,000 mg/day for an average sized horse.

Cosequin ASU is supplied in a 1300 gram container of tasty powder.

Cosequin ASU contains Glucosamine Hydrochloride, Low Molecular Weight Sodium Chondroitin Sulfate, and Avocado/Soybean Unsaponifiables.

FEEDING DIRECTIONS: INITIALLY FOR THE FIRST 2- 4 WEEKS FEED 2 SCOOPS DAILY(16.1GRAM SCOOP INCLUDED) FOR HORSES WEIGHING 600 TO 1200lbs, THEN REDUCE TO 1 SCOOP DAILY FOR LONG TERM FEEDING


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